"Not that there's anything to feel awkward about. She's just a female duplicate of your childhood friend / ex-boyfriend who you've barely spoken to outside of stressful situations and/or gatherings with lots of other people that limited the necessity for direct interaction."
This comic was slightly tricky for me to write, as I had trouble making it clear that the concern was just Ellen not wanting to turn into a guy, as opposed to giving the impression that it would be bad if she did for some reason. That might sound like a simple distinction, but comic panels are sorta like Twitter. You have limited space to make your point, and it's easy to run out of room and lose clarity as a result.
Granted, that's a thing that will no doubt get elaborated on later, but I didn't want to give the wrong impression only to have to clarify it later, either.